Question

Semaglutide vs tirzepatide: which is stronger?

✓Last reviewed · Written by Dr. George Grunberger · Medical review: pending — clinician review in progress · How we review

Short answer

Tirzepatide (Zepbound, Mounjaro) produced more average weight loss than semaglutide 2.4 mg (Wegovy) in head-to-head research. Semaglutide has more labeled outcome indications (heart, kidney, MASH). Wegovy HD 7.2 mg narrows the gap.

General information based on official labels. Your prescriber or pharmacist can advise on your situation.

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