Reference

GLP-1 and diabetes glossary

14 plain-English definitions of the terms you will meet on labels, in trials and at the pharmacy.

✓Last reviewed · Written by Dr. George Grunberger · Medical review: pending — clinician review in progress · How we review
A1C
A blood test showing average blood sugar over about 3 months.
Basal insulin
Long-acting insulin that covers background needs between meals and overnight.
BMI
Body mass index — weight in kilograms divided by height in metres squared.
Boxed warning
The FDA's strongest label warning.
Compounded drug
A drug mixed by a pharmacy for a patient; not FDA-approved.
GIP
Glucose-dependent insulinotropic polypeptide — a gut hormone targeted by tirzepatide.
GLP-1
Glucagon-like peptide-1 — a gut hormone that raises insulin, lowers appetite and slows digestion.
Half-life
Time for the amount of a drug in the body to fall by half.
Hypoglycemia
Low blood sugar.
MASH
Metabolic dysfunction-associated steatohepatitis — a form of fatty liver disease.
MTC
Medullary thyroid carcinoma — the cancer named in GLP-1 boxed warnings.
Off-label
Use of a drug for a purpose not on its approved label.
Prior authorization
Insurer approval needed before a drug is covered.
Titration
Gradual dose increases to improve tolerance.

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