Insulin degludec: Tresiba
insulin degludec · Ultra-long-acting (basal) insulin · Novo Nordisk
In short
Tresiba (insulin degludec) is an ultra-long-acting (basal) insulin made by Novo Nordisk, used for basal blood sugar control in diabetes (adults and children 1+). Schedule: once daily. It is prescription-only in the US and Canada.
FormPens (U-100, U-200), vials
How oftenOnce daily
United StatesFDA-approved; unbranded insulin degludec is available.
CanadaAvailable in Canada.
PrescriptionRequired
What it is used for
- Basal blood sugar control in diabetes (adults and children 1+)
Tresiba dosage
Per the official label. Your prescriber sets your dose — never change it on your own.
| 1Dose | Individualized in units; flexible timing, at least 8 hours between doses |
|---|
How to take it
Under the skin once daily.
Storage
Unopened: refrigerate. In use: up to 56 days.
How long it works compared with other insulins
Side effects
Common
- Low blood sugar (hypoglycemia)
- Injection-site reactions
- Weight gain
- Lipodystrophy or skin thickening at repeated injection sites
Serious — get medical help
- Severe hypoglycemia (confusion, seizures, loss of consciousness)
- Low potassium (hypokalemia)
- Fluid retention and heart failure when combined with thiazolidinediones
- Serious allergic reactions
Who should not use it
- During an episode of low blood sugar
- Never share pens or needles, even if the needle is changed
- Do not switch insulin type, brand or concentration without your prescriber
Cost
See $35 programs.
How to buy Tresiba legally
- Get a prescription from your doctor or a licensed telehealth provider.
- Fill it at a licensed pharmacy, or through the manufacturer's self-pay pharmacy.
- Verify any online pharmacy first (US: safe.pharmacy; Canada: your provincial pharmacy college register).
Also searched as: Tresiba, degludec, Tresiba FlexTouch, ultra long-acting insulin
Sources
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