Comparison

Mounjaro vs Ozempic for type 2 diabetes

✓Last reviewed · Written by Dr. George Grunberger · Medical review: pending — clinician review in progress · How we review

Quick answer

Mounjaro (tirzepatide) vs Ozempic (semaglutide) for type 2 diabetes: A1C, weight, doses and cost. Mounjaro tends to lower A1C and weight more on average; Ozempic has labeled heart and kidney outcome benefits. Prescribers weigh both.

Side by side

Mounjaro compared with Ozempic
FeatureMounjaroOzempic
MoleculeTirzepatide (GIP + GLP-1)Semaglutide (GLP-1)
Dose range2.5–15 mg weekly0.25–2 mg weekly
Kidney/heart indicationsNot on the US label for theseYes (CV events; CKD progression)
GenericNoneCanada only (2026)

Which one is right for you?

Mounjaro tends to lower A1C and weight more on average; Ozempic has labeled heart and kidney outcome benefits. Prescribers weigh both.

Both are prescription medicines. Which one fits depends on your diagnosis, history and coverage — decide with your prescriber.

Sources

Checked against these primary sources on .

GLP-1 & incretin medicinesMounjarotirzepatide · Once weeklyGLP-1 & incretin medicinesOzempic (injection)semaglutide · Once weeklyToolCompare any two medicines
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